Fertility preservation provision in the NHS in Scotland: guidance

Annex A

Relevant documents

The following guidelines/documents include some relevant information/detail on fertility preservation:

British Fertility Society guideline:

Yasmin E, Balachandren N, Davies MC, et al. Fertility preservation for medical reasons in girls and women: British fertility society policy and practice guideline. Hum Fertil (Camb) 2018; 21(1): 3-26.

ESHRE guideline:

ESHRE Guideline Group on Female Fertility Preservation, Anderson RA, Amant F, Braat D, D’Angelo A, Chuva de Sousa Lopes SM, Demeestere I, Dwek S, Frith L, Lambertini M et al. ESHRE guideline: female fertility preservation. Hum Reprod Open 2020;2020: hoaa052.

ESMO guideline:

Lambertini M, Peccatori FA, Demeestere I, Amant F, Wyns C, Stukenborg JB, Paluch-Shimon S, Halaska MJ, Uzan C, Meissner J et al. Fertility preservation and post-treatment pregnancies in post-pubertal cancer patients: ESMO Clinical Practice Guidelines. Ann Oncol 2020;31: 1664-1678.

PanCareLIFE consortium documents:

Mulder RL, Font-Gonzalez A, Hudson MM, van Santen HM, Loeffen EAH, Burns KC, Quinn GP, van Dulmen-den Broeder E, Byrne J, Haupt R et al. Fertility preservation for female patients with childhood, adolescent, and young adult cancer: recommendations from the PanCareLIFE Consortium and the International Late Effects of Childhood Cancer Guideline Harmonization Group. Lancet Oncol 2021;22: e45-e56.

Mulder RL, Font-Gonzalez A, Green DM, Loeffen EAH, Hudson MM, Loonen J, Yu R, Ginsberg JP, Mitchell RT, Byrne J et al. Fertility preservation for male patients with childhood, adolescent, and young adult cancer: recommendations from the PanCareLIFE Consortium and the International Late Effects of Childhood Cancer Guideline Harmonization Group. Lancet Oncol 2021;22: e57-e67.

American Society of Clinical Oncology guidance (ASCO):

Oktay K, Harvey BE, Partridge AH, et al. Fertility Preservation in Patients With Cancer: ASCO Clinical Practice Guideline Update. J Clin Oncol 2018: JCO2018781914.

Gender identity healthcare protocol for Scotland (September 2024)

NICE Clinical Guideline 156 Fertility: assessment and treatment of people with fertility problems (2013) http://guidance.nice.org.uk/CG156

RCOG Pregnancy and Breast Cancer Green–top Guideline No. 12 (2011) https://www.rcog.org.uk/globalassets/documents/guidelines/gtg_12.pdf

du Fossé NA, van der Hoorn MLP, van Lith JMM, le Cessie S, and Lashley EELO. Advanced paternal age is associated with an increased risk of spontaneous miscarriage: a systematic review and meta-analysis. Human Reproduction Update, Vol.26, No.5, pp. 650–669, 2020

Greenberg DR, Khandwala YS, Lu Y, Stevenson DK, Shaw GM and Eisenberg ML. Disease burden in offspring is associated with changing paternal demographics in the United States. SSN: 2047-2919 ANDROLOGY

Donnez J, Dolmans MM. Fertility Preservation in Women. N Engl J Med 2017; 377(17): 1657-65.

Picton HM, Wyns C, Anderson RA, et al. A European perspective on testicular tissue cryopreservation for fertility preservation in prepubertal and adolescent boys. Hum Reprod 2015; 30(11): 2463-75.

Partridge A. H., Niman S. M., Ruggeri M., Peccatori F. A., Azim H. A., Jr., Colleoni M., Saura C., Shimizu C., Saetersdal A. B., Kroep J. R., Mailliez A., Warner E., Borges V. F., Amant F., Gombos A., Kataoka A., Rousset-Jablonski C., Borstnar S., Takei J., Lee J. E., Walshe J. M., Ruiz-Borrego M., Moore H. C. F., Saunders C., Bjelic-Radisic V., Susnjar S., Cardoso F., Smith K. L., Ferreiro T., Ribi K., Ruddy K., Kammler R., El-Abed S., Viale G., Piccart M., Korde L. A., Goldhirsch A., Gelber R. D., Pagani O., International Breast Cancer Study G., Collaborators P. T. 2023. Interrupting Endocrine Therapy to Attempt Pregnancy after Breast Cancer. N Engl J Med,388, 1645-1656.

HFEA website information regarding fertility preservation for all patients: https://www.hfea.gov.uk/treatments/fertility-preservation/

HFEA information specific to transgender individuals https://www.hfea.gov.uk/treatments/fertility-preservation/information-for-trans-and-non-binary-people-seeking-fertility-treatment/